Found: The dial in the brain that controls the immune system

https://www.nature.com/articles/d41586-024-01259-2

Scientists have long known that the brain plays a part in the immune system — but how it does so has been a mystery. Now, scientists have identified cells in the brainstem that sense immune cues from the periphery of the body and act as master regulators of the body’s inflammatory response.

doi: https://doi.org/10.1038/d41586-024-01259-2

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"author": "Giorgia Guglielmi",
"date": "2024-05-01T00:00:00.000Z",
"description": "Scientists identify the brain cells that regulate inflammation, and pinpoint how they keep tabs on the immune response.",
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"title": "Found: the dial in the brain that controls the immune system",
"description": "Scientists have long known that the brain plays a part in the immune system — but how it does so has been a mystery. Now, scientists have identified cells in the brainstem that sense immune cues from the...",
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"content": "<div>\n <article>\n <div>\n <p>Scientists have long known that <a target=\"_blank\" href=\"https://doi.org/10.1038/d41586-023-00509-z\">the brain plays a part in the immune system</a> — but how it does so has been a mystery. Now, scientists have identified cells in the brainstem that sense <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-021-01396-y\">immune cues from the periphery of the body</a> and act as master regulators of the body’s <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-024-00871-6\">inflammatory response</a>.</p>\n <p><em>doi: https://doi.org/10.1038/d41586-024-01259-2</em></p>\n <div><h2 id=\"Bib1\">References</h2></div>\n <h2 id=\"related-articles\">Related Articles</h2>\n <ul>\n <li>\n <p>\n <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-023-00509-z\">\n <img src=\"https://media.nature.com/lw100/magazine-assets/d41586-024-01259-2/d41586-024-01259-2_24096670.jpg\" />\n Your brain could be controlling how sick you get — and how you recover\n </a>\n </p>\n </li>\n <li>\n <p>\n <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-022-01502-8\">\n <img src=\"https://media.nature.com/lw100/magazine-assets/d41586-024-01259-2/d41586-024-01259-2_24045344.jpg\" />\n Guardians of the brain: how a special immune system protects our grey matter\n </a>\n </p>\n </li>\n <li>\n <p>\n <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-024-00169-7\">\n <img src=\"https://media.nature.com/lw100/magazine-assets/d41586-024-01259-2/d41586-024-01259-2_26671374.jpg\" />\n Can autoimmune diseases be cured? Scientists see hope at last\n </a>\n </p>\n </li>\n <li>\n <p>\n <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-023-00584-2\">\n <img src=\"https://media.nature.com/lw100/magazine-assets/d41586-024-01259-2/d41586-024-01259-2_24096666.jpg\" />\n Anxiety can be created by the body, mouse heart study suggests\n </a>\n </p>\n </li>\n</ul>\n <h2 id=\"subjects\">Subjects</h2>\n <ul>\n <li>\n <a target=\"_blank\" href=\"https://www.nature.com/subjects/brain\">Brain</a>\n </li>\n <li>\n <a target=\"_blank\" href=\"https://www.nature.com/subjects/immunology\">Immunology</a>\n </li>\n <li>\n <a target=\"_blank\" href=\"https://www.nature.com/subjects/neuroscience\">Neuroscience</a>\n </li>\n</ul>\n <section>\n <h2 id=\"tablist-heading\">Latest on:</h2>\n <ul>\n <li>\n <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-024-01259-2#latest-content-0-container\">Brain</a>\n </li>\n <li>\n <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-024-01259-2#latest-content-1-container\">Immunology</a>\n </li>\n <li>\n <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-024-01259-2#latest-content-2-container\">Neuroscience</a>\n </li>\n </ul>\n <section>\n <ul>\n <li>\n <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-026-02356-0\">\n <img src=\"https://images.nature.com/w140h79/magazine-assets/d41586-026-02356-0/d41586-026-02356-0_53043332.jpg\" />\n <p>Brains of male and female mice recover differently from ketamine</p>\n <p><span>Research Highlight</span> <span>31 JUL 26</span></p>\n </a>\n </li>\n <li>\n <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-026-02311-z\">\n <img src=\"https://images.nature.com/w140h79/magazine-assets/d41586-026-02311-z/d41586-026-02311-z_53030010.jpg\" />\n <p>All living things emit a faint glow. 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